Intracerebral metastases medical therapy
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Intracerebral metastases Microchapters |
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Differentiating Intracerebral Metastases from other Diseases |
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Diagnosis |
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Treatment |
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Intracerebral metastases medical therapy On the Web |
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Overview
Medical Therapy
Symptomatic: Corticosteroids are given to limit the effects of peritumoral edema. Hyperosmolar agents (eg mannitol) can be given to decrease ICP and anticonvulsants are given to prevent seizures. Recently, methylphenidate and donepezil have been used to improve cognition, mood and quality of life.
Therapeutic: Radiation (whole brain external beam or stereotactic for smaller masses), chemotherapy and surgical resection are done to prolong survival and palliate symptoms. Other than germ cell tumors, leukemias and lymphomas, palliation is the rule and curative therapy is the subject of case reports.