Zollinger-Ellison syndrome medical therapy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Zollinger-Ellison syndrome Microchapters
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Medical Therapy

• Proton pump inhibitors: (such as omeprazole and lansoprazole) and histamine H2-receptor antagonists (such as famotidine and ranitidine) are used to slow down acid secretion. Usual drugs include esomeprazole (Nexium), lansoprazole (Prevacid), pantoprazole (Protonix) and omeprazole (Prilosec).
• Chemotherapy: For those the tumor can not be surgically removed, chemotherapy is available. The drugs include streptozotocin (Zanosar), 5-fluorouracil (Adrucil) and doxorubicin (Doxil).
• Octreotide can be used to slow down acid secretion.