Toxic multinodular goiter natural history, complications and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Natural History
Complications
Heart complications:
- Congestive heart failure
- Irregular heartbeat (atrial fibrillation)
- Rapid heart rate
Other complications:
- Bone loss leading to osteoporosis
Thyroid crisis or storm is an acute worsening of hyperthyroidism symptoms. It may occur with infection or stress. Thyroid crisis may cause:
- Abdominal pain
- Decreased mental alertness
- Fever
People with this condition need to go to the hospital right away.
Complications of having a very large goiter may include difficulty breathing. This is due to pressure on the airway passage that lies behind the thyroid.
Prognosis
Because toxic nodular goiter is mainly a disease of the elderly, other chronic health problems may influence the outcome of this condition. An elderly person may be less able to tolerate the effect of hyperthyroidism on the heart.