Hyperpituitarism
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| Hyperpituitarism | |
| ICD-10 | E22 |
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| ICD-9 | 253.1 |
| MeSH | D006964 |
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Hyperpituitarism Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Hyperpituitarism On the Web |
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American Roentgen Ray Society Images of Hyperpituitarism |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Clinical manifestations
Depending on the cell type(s) affected, clinical manifestations of hormone excess may include:
- Hyperprolactinaemia
- Cushing's disease
- Precocious puberty
- Gigantism or Acromegaly
- Hyperthyroidism (rare)
Associated conditions
When there is an enlargement of the pituitary tissue, hyperpituitarism is often associated with:
- Visual field defects, classically bitemporal hemianopia
- Radiographic abnormalities of the sella turcica, such as sellar expansion, bony erosion and disuption of the diaphragma sellae
- Increased intracranial pressure
Symptoms
Symptoms caused by hormone excess and associated mass effects include:
- Headache
- Visual field loss or Double vision
- Excessive sweating
- Hoarseness
- Milk secretion from breast
- Sleep apnea
- Carpal tunnel syndrome
- Joint pain and limitation of motion
- Muscle weakness
- Numbness or tingling of skin