Hemolytic-uremic syndrome natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

Natural History

Complications

About one-third of persons with hemolytic-uremic syndrome have abnormal kidney function many years later, and a few require long-term dialysis. Another 8% of persons with hemolytic uremic syndrome have other lifelong complications, such as high blood pressure, seizures, blindness, paralysis, and the effects of having part of their colon removed.==Prognosis== With aggressive treatment > 90% survive acute phase. About 9% may develop end stage renal disease. The overall mortality rate from HUS is 5-15%. Older children and adults have a worse prognosis.[1]

References

  1. Chu P, Hemphill RR (2004). "222: Acuired hemolytic anemia". In Tintinalli JE, Kelen GD, Stapczynski JS. Emergency Medicine: A Comprehensive Study Guide (6th Edition ed.). New York, NY: McGraw-Hill. ISBN 0-07-138875-3

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