Loeffler syndrome

Loeffler's syndrome
Classification and external resources
File:Eosinophil.png
Eosinophil
ICD-10	J82
ICD-9	518.3
DiseasesDB	7580
MedlinePlus	000105
MeSH	D011657

WikiDoc Resources for Loeffler syndrome
Articles
Most recent articles on Loeffler syndrome Most cited articles on Loeffler syndrome Review articles on Loeffler syndrome Articles on Loeffler syndrome in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Loeffler syndrome Images of Loeffler syndrome Photos of Loeffler syndrome Podcasts & MP3s on Loeffler syndrome Videos on Loeffler syndrome
Evidence Based Medicine
Cochrane Collaboration on Loeffler syndrome Bandolier on Loeffler syndrome TRIP on Loeffler syndrome
Clinical Trials
Ongoing Trials on Loeffler syndrome at Clinical Trials.gov Trial results on Loeffler syndrome Clinical Trials on Loeffler syndrome at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Loeffler syndrome NICE Guidance on Loeffler syndrome NHS PRODIGY Guidance FDA on Loeffler syndrome CDC on Loeffler syndrome
Books
Books on Loeffler syndrome
News
Loeffler syndrome in the news Be alerted to news on Loeffler syndrome News trends on Loeffler syndrome
Commentary
Blogs on Loeffler syndrome
Definitions
Definitions of Loeffler syndrome
Patient Resources / Community
Patient resources on Loeffler syndrome Discussion groups on Loeffler syndrome Patient Handouts on Loeffler syndrome Directions to Hospitals Treating Loeffler syndrome Risk calculators and risk factors for Loeffler syndrome
Healthcare Provider Resources
Symptoms of Loeffler syndrome Causes & Risk Factors for Loeffler syndrome Diagnostic studies for Loeffler syndrome Treatment of Loeffler syndrome
Continuing Medical Education (CME)
CME Programs on Loeffler syndrome
International
Loeffler syndrome en Espanol Loeffler syndrome en Francais
Business
Loeffler syndrome in the Marketplace Patents on Loeffler syndrome
Experimental / Informatics
List of terms related to Loeffler syndrome

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]

Synonyms and keywords: Löffler's syndrome

Overview

Loeffler's syndrome is a disease in which eosinophils accumulate in the lung in response to a parasitic infection.

Historical perspective

It was first described in 1932 by Wilhelm Löffler in cases of eosinophilic pneumonia caused by the parasites Ascaris lumbricoides, Strongyloides stercoralis and the hookworms Ancylostoma duodenale and Necator americanus.

Pathophysiology

Infecting larvae reach the lungs via the bloodstream, penetrate into alveoli, and ascend the airways before descending the alimentary tract into the small bowel. Alveolar penetration triggers off an allergic reaction leading to pulmonary eosinophilia.

Causes

• Ascaris lumbricoides
• Strongyloides stercoralis
• Ancylostoma duodenale
• Necator americanus