Aphthous ulcer differential diagnosis

Aphthous ulcer Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Differential Diagnosis

• Infections
  • Recurrent infection with herpesvirus
  • HIV infection, Intraoral infections (candidiasis, hairy leukoplakia), or neoplasms (Kaposi’s sarcoma, lymphoma).

• Rheumatic diseases
  • Behçet’s syndrome
  • Reactive arthritis (Reiter’s syndrome)
  • Sweet’s syndrome

• Cutaneous diseases
  • Erythema multiforme
• Hematologic diseases
  • Cyclic neutropenia
  • Leukemias

• Gastro-Intestinal diseases
  • Gluten-sensitive enteropathy
  • Inflammatory bowel disease (ulcerative colitis, Crohn’s disease)
• Drugs
  • Nonsteroidal antiinflammatory drugs
  • Beta-blockers
  • Nicorandil (Ikorel)
  • Alendronate (Fosamax)

References

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