Biliary atresia history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Prolonged jaundice that is resistant to phototherapy and/or exchange transfusions should prompt a search for secondary causes.
History and Symptoms
Initially, the symptoms are indistinguishable from neonatal jaundice, a common phenomenon.
Symptoms are usually evident between two and six weeks after birth.
Infants and children with biliary atresia have progressive cholestasis with all the usual concomitant features:
- Jaundice
- Pale stools
- Dark urine
- Pruritus
- Malabsorption with growth retardation
- Eventually cirrhosis with portal hypertension.
- Swollen abdominal region(Ascites) and
- Large hardened liver (which may or may not be observable by the naked eye).