Meningitis medical therapy

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Meningitis Main Page

Patient Information

Overview

Causes

Classification

Viral Meningitis
Bacterial Meningitis
Fungal Meningitis

Differential Diagnosis

Diagnosis

Treatment

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]

Overview

Medical Therapy

Empiric Treatment

Shown below is a table summarizing the preferred and alternative empiric treatment for meningitis.
Characteristics of the Patient Possible Pathogens Preferred Treatment Duration of Treatment Alternative Treatment
Immunocompentent patient

Age<50

Streptococcus pneumonia

Nisseria meningitis

Hemophilus influenzae

Vancomycin

Loading dose:25-35 mg/kg, then 15-20 mg/kg Q8-12H

Trough concentration: 20mcg/mL

+

Ceftriaxone

2 g IV Q12H

Stop or adjust treatment choice and duration when the results of the lumbar puncture are out In case of penicillin allergy:

Chloramphenicol

+

Vancomycin

Immunocompentent patient

Age>50

Immunocompromised patient
Patient with history of penetrating head trauma or neurosurgery
Shunt infection

Pathogen Specific Treatment

References


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