Kikuchi disease natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Natural History

Course of the disease is generally benign and self-limiting. Lymphadenopathy most often resolves over several weeks to six months. Recurrence rate is about 3%.

Prognosis

• Kikuchi's disease is a self limiting illness.

• In most reported cases, it is common for the debilitating symptoms to last for half a year; however, the disease does return to some patients after time.

• Mortality is extremely rare and usually due to hepatic, respiratory, or cardiac failure.