Bornholm disease pathophysiology
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Bornholm disease is a disease caused by one of the group B coxsackie viruses and is less often caused by a group A coxsackie virus or an echovirus, causing pain in the muscles of the chest that join ribs together.
Pathophysiology
Group B coxsackieviruses are transmitted from person to person by fecal-oral contamination or direct mouth to mouth contact. Other people become infected with the virus if they touch contaminated items then put their fingers in their mouth before washing them properly. Contaminated items can include soiled diapers, shared toys and toilets. Epidemic pleurodynia is contagious and occurs in clusters, meaning many people in an area get it around the same time.
The virus that causes devil's grip is picornavirus. It is spread by contact and epidemics usually occur during warm weather in temperate regions and at any time in the tropics. It can also be spread through saliva and feces[1]. Once inside the body, the coxsackie viruses multiply in the throat and intestines then spread into the bloodstream. At this point, the body's immune defenses often can limit the infection and prevent the person from developing symptoms. If the immune defenses are less successful, the person starts developing symptoms.