Bartonellosis medical therapy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Medical Therapy
Pharmacotherapy
Treatment of infections caused by Bartonella species.[1][2]
| Disease | Adults | Children |
|---|---|---|
| Cat scratch disease | no recommendation | no recommendation |
| Retinitis | Doxycycline + Rifampin | unknown |
| Trench fever or chronic bacteremia by B.quintana | Doxycycline + Gentamicin | unknown |
| Bacillary angiomatosis | Erythromycin or Doxycycline | Erythromycin |
| Peliosis hepatis | Erythromycin or Doxycycline | Erythromycin |
| Endocarditis | Doxycycline + Gentamicin + Rifampin or Ceftriaxone + Gentamicin | |
| Carrión´s disease (acute phase) | Ciprofloxacin or Chloramphenicol | Chloramphenicol + beta-lactam |
| Carrión´s disease (chronic phase: Verruga peruana) | Rifampin or macrolides | Rifampin or macrolides |
While some authorities recommend the use of azithromycin,[3] it's difficult to gauge what, if any significant benefit, is afforded given the often self-limiting course in patients with intact immune function.
References
- ↑ Rolain JM, Brouqui P, Koehler JE, Maguina C, Dolan MJ, Raoult D (2004). "Recommendations for treatment of human infections caused by Bartonella species". Antimicrob. Agents Chemother. 48 (6): 1921–33. doi:10.1128/AAC.48.6.1921-1933.2004. PMC 415619. PMID 15155180. Unknown parameter
|month=ignored (help) - ↑ Blanco JR, Raoult D (2005). "[Diseases produced by Bartonella]". Enferm. Infecc. Microbiol. Clin. (in Spanish; Castilian). 23 (5): 313–9, quiz 320. PMID 15899181. Unknown parameter
|month=ignored (help) - ↑ Bass JW; Freitas BC; Freitas AD; et al. (1998). "Prospective randomized double blind placebo-controlled evaluation of azithromycin for treatment of cat-scratch disease". Pediatr. Infect. Dis. J. 17 (6): 447–52. doi:10.1097/00006454-199806000-00002. PMID 9655532. Unknown parameter
|month=ignored (help); Unknown parameter|author-separator=ignored (help)