Toxoplasmosis medical therapy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Medical Therapy
Teatment is not needed for a healthy person who is not pregnant. Symptoms will usually go away within a few weeks. Treatment may be recommended for pregnant women or persons who have weakened immune systems [1].
Pharmacotherapy
Medications that are prescribed for acute Toxoplasmosis are:
- Pyrimethamine — an antimalarial medication.
- Sulfadiazine — an antibiotic used in combination with pyrimethamine to treat toxoplasmosis.
- clindamycin — an antibiotic. This is used most often for people with HIV/AIDS.
- spiramycin — another antibiotic. This is used most often for pregnant women to prevent the infection of their child.
(Other antibiotics such as minocycline have seen some use as a salvage therapy).
Medications that are prescribed for latent Toxoplasmosis are:
- atovaquone — an antibiotic that has been used to kill Toxoplasma cysts in situ in AIDS patients. [2]
- clindamycin — an antibiotic which, in combination with atovaquone, seemed to optimally kill cysts in mice.[3]
However, in latent infections successful treatment is not guaranteed, and some subspecies exhibit resistance.
References
- ↑ http://www.dpd.cdc.gov/dpdx/HTML/Toxoplasmosis.htm
- ↑ "Toxoplasmosis - treatment key research". NAM & aidsmap. 2005-11-02.
- ↑ Djurković-Djaković O, Milenković V, Nikolić A, Bobić B, Grujić J (2002). "Efficacy of atovaquone combined with clindamycin against murine infection with a cystogenic (Me49) strain of Toxoplasma gondii" (PDF). J Antimicrob Chemother. 50 (6): 981–7. doi:10.1093/jac/dkf251. PMID 12461021.