Primary amoebic meningoencephalitis laboratory findings

Primary amoebic meningoencephalitis Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

Primary amoebic meningoencephalitis is diagnosed using specific laboratory tests available in only a few laboratories in the United States. Because of the rarity of the infection and difficulty in initial detection, about 75% of diagnoses are made after the death of the patient. It can be diagnosed in the laboratory by detecting Naegleria fowleri organisms, nucleic acid, or antigen in cerebrospinal fluid (CSF), biopsy, or tissue specimens.