Oral candidiasis natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Natrual History, Complications and Prognosis

There are no sequela with appropriate antifungal therapy. In contrast, among immunocompromised patients with disseminated infections, the mortality rate is almost 50%.

Thrush in infants may be painful, but is rarely serious. Because of discomfort, it can interfere with eating. If it does not resolve on its own within 2 weeks, call your pediatrician. In adults, thrush that occurs in the mouth can be cured. However, the long-term outlook is dependent on your immune status and the cause of the immune deficit.

If you have a weakened immune system (for example, if you are HIV-positive or receiving chemotherapy), Candida can spread throughout your body, causing infection in your esophagus (esophagitis), brain (meningitis), heart (endocarditis), joints (arthritis), or eyes (endophthalmitis).