Barrett's esophagus future or investigational therapies

Barrett's Esophagus Microchapters
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Overview
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Causes
Differentiating Barrett's Esophagus from other Diseases
Epidemiology and Demographics
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Diagnostic Study of Choice
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Future or Investigational Therapies
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Overview

• Biomarkers

1. Can not be used to confirm the diagnosis of Barrett´s esophagus.
2. Can not be used to predict risk of progression.
3. Promissing for the future.

• Endoscopic Therapy

1. In patients with confirmed high-grade dysplasia with Barrett' esophagus it is more recommended to proceed with endoscopic eradication therapy with radiofrequency ablation (RFA), photodynamic therapy (PDT), or endoscopic mucosal resection (EMR) rather than surveillance.
2. In patients who have dysplasia in Barrett's esophagus associated with a visible mucosal irregularity it is recommended to proceed with endoscopic mucosal resection (EMR) to determine the T stage of the neoplasia.