Atrial septal defect ostium primum anatomy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S. [2]; Cafer Zorkun, M.D., Ph.D. [3]; Assistant Editor(s)-In-Chief: Kristin Feeney, B.S. [4]
Overview
Ostium primum defects usually occur due to the failure in fusion of the septum primum with the endocardial cushion.
Anatomy
- It occurs from the failure of fusion of the septum primum with the endocardial cushion.
- The endocardial cushion, is the portion of the heart where the atrial septum meets the ventricular septum and the mitral valve meets the tricuspid valve.
- It involves the inferior portion of the septum
- Due to this, these defects commonly occurs in association with other cardiac anomalies such as atrioventricular valves (the mitral valve and the tricuspid valve).
- The abnormalities of the atrioventricular valves include the cleft mitral valve, and the single atrioventricular valve (a single large, deformed valve that flows into both the right ventricle and the [left ventricle]]).
- These are usually large sized defects when compared to the secundum defects
- Endocardial cushion defects are the most common congenital heart defect that is associated with Down's syndrome.