Pemberton's sign
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Pemberton's sign[1] is the development of facial plethora, distended neck and head superficial veins, inspiratory stridor and elevation of the jugular venous pressure (JVP) upon raising of the patient's both arms above his/her head simultaneously, as high as possible (Pemberton's maneuver).
Causes
A positive Pemberton's sign is a sign of superior vena cava syndrome, possibly from a mass in the mediastinum, usually caused by a tumor or goiter.
Apical lung cancers often cause a positive Pemberton's sign and a high index of suspicion should be maintained in patients with symptoms of dyspnea and facial plethora with an extensive smoking history.
References
- ↑ Pemberton HS. Sign of submerged goitre. Lancet 1946;251:509.