Tuberous sclerosis MRI

Tuberous sclerosis Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

The tubers are typically triangular in configuration, with the apex pointed towards the ventricles, and are thought to represent foci of abnormal neuronal migration. The T2 signal abnormalities may subside in adulthood, but will still be visible on histopathological analysis. On magnetic resonance imaging, TSC patients can exhibit other signs consistent with abnormal neuron migration (radial white matter tracts hyperintense on T2WI, heterotopic gray matter).

MRI

MRI of the brain in a patient with TSC.