Familial mediterranean fever natural history, complications and prognosis
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Familial Mediterranean Fever Microchapters |
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Differentiating Familial Mediterranean Fever from other Diseases |
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Diagnosis |
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Treatment |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Complications
AA-amyloidosis with renal failure is a complication and may develop without overt crises. AA (amyloid protein) is produced in very large quantities during attacks and at a low rate between them, and accumulates mainly in the kidney, as well as the heart, spleen, gastrointestinal tract and the thyroid.[1]
There appears to be an increase in the risk for developing particular vasculitis-related diseases (e.g. Henoch-Schönlein purpura), spondylarthropathy, prolonged arthritis of certain joints and protracted myalgia.[1]
Prognosis
There is no known cure for familial mediterranean fever. Most people continue to have attacks, but the number and severity of attacks is different from person to person.