Familial mediterranean fever medical therapy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Attacks are self-limiting, and require analgesia and non-steroidal anti-inflammatory drugs (such as diclofenac).[1]
Since the 1970s, colchicine, a drug otherwise mainly used in gout, has been shown to decrease attack frequency in FMF patients. The exact way in which colchicine suppresses attacks is unclear. While this agent is not without side-effects (such as abdominal pain and muscle pains), it may markedly improve quality of life in patients. The dosage is typically 1-2 mg a day. Development of amyloidosis is delayed with colchicine treatment. Interferon is being studied as a therapeutic modality.[1]