Tetanus historical perspective

Revision as of 14:22, 27 March 2013 by Ochuko Ajari (talk | contribs)
Jump to navigation Jump to search

Tetanus Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Tetanus from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Xray

CT scan

MRI

Ultrasound

Other Imaging Studies

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Tetanus historical perspective On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Tetanus historical perspective

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Tetanus historical perspective

CDC on Tetanus historical perspective

Tetanus historical perspective in the news

Blogs on Tetanus historical perspective

Directions to Hospitals Treating Tetanus

Risk calculators and risk factors for Tetanus historical perspective

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Historical Perspective

Although records from antiquity (5th century BCE) contain clinical descriptions of tetanus, it was Carle and Rattone in 1884 who first produced tetanus in animals by injecting them with pus from a fatal human tetanus case. During the same year, Nicolaier produced tetanus in animals by injecting them with samples of soil. In 1889, Kitasato isolated the organism from a human victim, showed that it produced disease when injected into animals, and reported that the toxin could be neutralized by specific antibodies. In 1897, Nocard demonstrated the protective effect of passively transferred antitoxin, and passive immunization in humans was used for treatment and prophylaxis during World War I. Tetanus toxoid was developed by Descombey in 1924. It was first widely used during World War II.

Famous Tetanus Victims

  • George Montagu - English ornithologist; contracted tetanus when he stepped on a nail.
  • Joe Powell - English footballer; contracted following amputation of a badly broken arm.
  • John A. Roebling - Civil Engineer and Architect famous for his bridge designs, particularly the Brooklyn Bridge; contracted following amputation of his foot due to an injury caused by a ferry when it crashed into a wharf.
  • George Crockett Strong - Union brigadier general in the American Civil War; from wounds sustained in the assault against Fort Wagner on Morris Island, South Carolina.
  • Fred Thomson - silent film actor; stepped on a nail.
  • Johann Tserclaes, Count of Tilly; wounded by a cannon ball in the Battle of Rain.
  • Traveller - General Robert E. Lee's favorite horse; stepped on a nail.
  • John Thoreau; brother of Henry David Thoreau

References

Template:WH Template:WS