Dermatofibroma pathophysiology

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Pathophysiology

Some physicians and researchers believe dermatofibromas form as a reaction to previous injuries such as insect bites or thorn pricks.
Dermatofibromas are composed of disordered collagen laid down by fibroblasts.

Neoplasm	CD34^[1]	Stromelysin-3^[2]	Factor XIIIa^[3]
Dermatofibroma	+	+	+
Dermatofibrosarcoma protuberans	+	-	-

↑ Invalid <ref> tag; no text was provided for refs named Bolognia
↑ Kim HJ, Lee JY, Kim SH; et al. (2007). "Stromelysin-3 expression in the differential diagnosis of dermatofibroma and dermatofibrosarcoma protuberans: comparison with factor XIIIa and CD34". Br. J. Dermatol. 157 (2): 319–24. doi:10.1111/j.1365-2133.2007.08033.x. PMID 17596171. Unknown parameter |month= ignored (help)
↑ http://emedicine.medscape.com/article/1056742-overview