Portal hypertension pathophysiology

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Portal Hypertension Microchapters
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Overview

Portal venous pressure is determined by portal blood flow and portal vascular resistance. Increased portal vascular resistance is often the main factor responsible for it. The consequences of portal hypertension are due to blood being forced down alternate channels by the increased resistance to flow through the portal system. Due to formation of alternate channels initially some of the portal blood and later most of it is shunted directly to the systemic circularion bypassing the liver.