Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview The presence of elastase in the blood serum is caused by serine proteinase hydrolyzing elastic occuring in the endothelial cells, macrophages, and granulocytes
Reference Range
In Plasma 60-110 ng/ml
In Pleural Effusion 480-2900 ng/ml
Causes of increased elastase in blood serum[1] [2] Common Causes Causes by Organ System
Cardiovascular
No underlying causes
Chemical/Poisoning
No underlying causes
Dental
No underlying causes
Dermatologic
No underlying causes
Drug Side Effect
No underlying causes
Ear Nose Throat
No underlying causes
Endocrine
No underlying causes
Environmental
No underlying causes
Gastroenterologic
No underlying causes
Genetic
No underlying causes
Hematologic
No underlying causes
Iatrogenic
No underlying causes
Infectious Disease
No underlying causes
Musculoskeletal/Orthopedic
No underlying causes
Neurologic
No underlying causes
Nutritional/Metabolic
No underlying causes
Obstetric/Gynecologic
No underlying causes
Oncologic
No underlying causes
Ophthalmologic
No underlying causes
Overdose/Toxicity
No underlying causes
Psychiatric
No underlying causes
Pulmonary
No underlying causes
Renal/Electrolyte
No underlying causes
Rheumatology/Immunology/Allergy
No underlying causes
Sexual
No underlying causes
Trauma
No underlying causes
Urologic
No underlying causes
Miscellaneous
No underlying causes
Causes in Alphabetical Order References
↑ Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
↑ Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X
↑ Donnelly, SC.; MacGregor, I.; Zamani, A.; Gordon, MW.; Robertson, CE.; Steedman, DJ.; Little, K.; Haslett, C. (1995). "Plasma elastase levels and the development of the adult respiratory distress syndrome". Am J Respir Crit Care Med . 151 (5): 1428–33. doi :10.1164/ajrccm.151.5.7735596 . PMID 7735596 . ↑ Hughes, SF.; Cotter, MJ.; Evans, SA.; Jones, KP.; Adams, RA. (2006). "Role of leucocytes in damage to the vascular endothelium during ischaemia-reperfusion injury". Br J Biomed Sci . 63 (4): 166–70. PMID 17201205 . ↑ Baines, KJ.; Simpson, JL.; Wood, LG.; Scott, RJ.; Gibson, PG. (2011). "Systemic upregulation of neutrophil α-defensins and serine proteases in neutrophilic asthma". Thorax . 66 (11): 942–7. doi :10.1136/thx.2010.157719 . PMID 21785157 .
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