WBR0063

Author	PageAuthor::William J Gibson
Exam Type	ExamType::USMLE Step 1
Main Category	MainCategory::Microbiology
Sub Category	SubCategory::Neurology, SubCategory::Infectious Disease
Prompt	[[Prompt::A 28 year old woman has developed an inflammatory disease causing demyelination of peripheral nerves. He began experiencing numbness in his toes which progressed to distal muscle weakness of his lower limb and has now progressed to include the entire lower limb and the distal upper limb. CSF findings include increased protein with a normal cell count. The patient is started on IV Ig. Which of the following describes the organism most likely to have infected this patient prior to his developing this condition?]]
Answer A	AnswerA::Comma shaped, oxidase positive, gram negative organism which grows at 42C.
Answer A Explanation	AnswerAExp::Correct - See Explanation
Answer B	AnswerB::Gram positive rod with tumbling motility
Answer B Explanation	AnswerBExp::Incorrect - This describes Listeria monocytogenes.
Answer C	AnswerC::Gram negative, urease positive rod.
Answer C Explanation	AnswerCExp::Incorrect - This describes Helicobacter Pylori.
Answer D	AnswerD::Gram positive, spore forming rod
Answer D Explanation	AnswerDExp::Incorrect - This describes Clostridium species and Baccilus anthracis.
Answer E	AnswerE::Lancet shaped, gram positive diplococci.
Answer E Explanation	AnswerEExp::Incorrect - This describes Strep. Pneumoniae.
Right Answer	RightAnswer::A
Explanation	[[Explanation::The patient in this vignette has Guillain-Barre syndrome, a progressive autoimmune demyelinating disease of peripheral nerves. Guillain-Barre is known to be preceded by Campylobacter Jejuni in particular. Campylobacter jejuni is a comma shaped, oxidase positive, gram negative organism which grows at 42C. Educational Objective: Guillain-Barre is known to be preceded by Campylobacter Jejuni, a Comma shaped, oxidase positive, gram negative organism with grows at 42C. Microbiology #Neurology Educational Objective: References: ]]
Approved	Approved::Yes
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