Porokeratosis

Porokeratosis
File:Porokeratosis DSAP.JPG
A porokeratosis lesion in a patient with disseminated superficial actinic porokeratosis.
DiseasesDB	31356
eMedicine	article/1059123
MeSH	D017499

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Porokeratosis is a specific disorder of keratinization that is characterized histologically by the presence of a cornoid lamella, a thin column of closely stacked, parakeratotic cells extending through the stratum corneum with a thin or absent granular layer.

Types

Porokeratosis may be divided into the following clinical types:

• Classic porokeratosis Mibelli
• Disseminated superficial actinic porokeratosis
• Disseminated superficial porokeratosis
• Porokeratosis palmaris et plantaris disseminata
• Linear porokeratosis
• Punctate porokeratosis

However, additional types have also been described:

• Porokeratosis plantaris discreta

Pathology

File:Porokeratosis - high mag.jpg

Micrograph of a case of porokeratosis showing a characteristic cornoid lamella (dark pink/red structure in the right/upper portion of the image). H&E stain.

Porokeratosis has a characteristic histomorphologic feature known as a cornoid lamella.

See also

• List of cutaneous conditions
• List of cutaneous conditions associated with increased risk of nonmelanoma skin cancer

References

Template:Genodermatoses-stub