Porokeratosis

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Evidence Based Medicine
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Clinical Trials
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Guidelines / Policies / Govt
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Commentary
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Definitions
Definitions of Porokeratosis
Patient Resources / Community
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Healthcare Provider Resources
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Experimental / Informatics
List of terms related to Porokeratosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Porokeratosis is a specific disorder of keratinization that is characterized histologically by the presence of a cornoid lamella, a thin column of closely stacked, parakeratotic cells extending through the stratum corneum with a thin or absent granular layer.

Types

Porokeratosis may be divided into the following clinical types:

• Classic porokeratosis Mibelli
• Disseminated superficial actinic porokeratosis
• Disseminated superficial porokeratosis
• Porokeratosis palmaris et plantaris disseminata
• Linear porokeratosis
• Punctate porokeratosis

However, additional types have also been described:

• Porokeratosis plantaris discreta

Pathology

File:Porokeratosis - high mag.jpg

Micrograph of a case of porokeratosis showing a characteristic cornoid lamella (dark pink/red structure in the right/upper portion of the image). H&E stain.

Porokeratosis has a characteristic histomorphologic feature known as a cornoid lamella.

References

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