Metabolic acidosis critical pathways

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Approach

Metabolic acidosis physician extender algorithm
Elevated anion gap? Yes No

Definition

  • Metabolic acidosis is a state in which the blood pH is less than 7.35 due to increased production of H+ by the body or the inability of the body to form bicarbonate (HCO3-) in the kidney.
  • Anion gap = [Na+] - [Cl-] - [HCO3-]
  • Normal reference range for anion gap (AG) is between 8 and 16 meq/L.[1][2]

References

  1. Benjamin Abelow (1998). Understanding acid-base. Baltimore: Williams & Wilkins. ISBN 0-683-18272-2.
  2. Rector, Floyd C.; Brenner, Barry M. (2008). Brenner & Rector's the kidney. Saunders Elsevier. ISBN 1-4160-3105-7.


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