WBR0202
| Author | [[PageAuthor::Ayokunle Olubaniyi, M.B,B.S [1]]] |
|---|---|
| Exam Type | ExamType::USMLE Step 1 |
| Main Category | MainCategory::Pathology |
| Sub Category | SubCategory::Oncology |
| Prompt | [[Prompt::A 12-year-old boy comes to the health center because he has had persistent fever and pain in his right leg for the past 2 months. He says that he recently added jogging to his weight-lifting workouts, and he started running 5 miles per day 2 weeks ago. He is 5 ft 7 inches tall and weighs 60kg. On physical examination, he has moderate tenderness over the diaphysis of the right leg. Additional tests were done which revealed a small, round, blue cell tumor, and a translocation between chromosomes 11 and 22. X-ray of the hip will most likely show which of the following?
A) “Double bubble” sign B) Codman’s triangle or sunburst appearance pattern C) “Onion-skin” appearance D) Glistering mass within the medullary cavity E) Normal findings]] |
| Answer A | AnswerA::Incorrect |
| Answer A Explanation | AnswerAExp::Double bubble sign is a feature of Osteoclastoma. The age range is between 20-40 years and it is usually located at the epiphysis of long bones. |
| Answer B | AnswerB::Incorrect |
| Answer B Explanation | AnswerBExp::This is a feature of Osteosarcoma. It affects men between ages 10-20 years. It is usually around the metaphysis of long bones. |
| Answer C | AnswerC::Correct |
| Answer C Explanation | AnswerCExp:: |
| Answer D | AnswerD::Incorrect |
| Answer D Explanation | AnswerDExp::This is a feature of Chondrosarcoma. It affects men between the ages 30-60. It is commonly found in the pelvis, spine, scapula, tibia, and femur. |
| Answer E | AnswerE::Incorrect |
| Answer E Explanation | AnswerEExp::Normal findings. |
| Right Answer | RightAnswer::C |
| Explanation | [[Explanation::Ewing’s sarcoma is a malignant small, round, blue cell tumor in which cancer cells are found in the bone or in soft biological tissue. It is a rare disease commonly prevalent among boys less than 15 years of age. The most common locations are: pelvis, femur, humerus, ribs and clavicle (collar bone). The characteristic appearance on X-ray is the “Onion-skin” appearance. Treatment is chemotherapy. Educational Objective: |
| Approved | Approved::No |
| Keyword | |
| Linked Question | Linked:: |
| Order in Linked Questions | LinkedOrder:: |