WBR0246

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Author [[PageAuthor::Rim Halaby, M.D. [1]]]
Exam Type ExamType::USMLE Step 1
Main Category MainCategory::Pathology
Sub Category SubCategory::Gastrointestinal, SubCategory::Gastrointestinal
Prompt [[Prompt::A 62-year-old male complains of four months history of worsening abdominal pain. The pain is localized in the upper abdominal area and it is dull in nature, constant and progressively increasing in intensity independently from food intake or change in posture. Review of system is significant for several months history of increasing fatigue and weight loss. CT scan reveals a mass in the stomach. Endoscopy guided biopsy of the mass reveals extensive aggregation of spindle cells highly suspicious of gastrointestinal stromal tumor (GIST). Immunohistochemistry of which of the following is diagnostic of GIST?]]
Answer A AnswerA::C kit gene
Answer A Explanation AnswerAExp::
Answer B AnswerB::Ret gene
Answer B Explanation AnswerBExp::
Answer C AnswerC::Abl gene
Answer C Explanation AnswerCExp::
Answer D AnswerD::Ras gene
Answer D Explanation AnswerDExp::
Answer E AnswerE::C myc gene
Answer E Explanation AnswerEExp::
Right Answer RightAnswer::E
Explanation [[Explanation::

Educational Objective:
References: ]]

Approved Approved::No
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