WBR0310

Author	PageAuthor::William J Gibson
Exam Type	ExamType::USMLE Step 1
Main Category	MainCategory::Biochemistry, MainCategory::Genetics
Sub Category	SubCategory::General Principles
Prompt	[[Prompt::A 25 year old girl presents to her primary care physician complaining of generalized weakness. She reports that the weakness is particularly pronounced in her hands, feet and neck. Furthermore, she reports some difficulty swallowing the multivitamins she takes daily. On further questioning, she admits to greater than normal daytime sleepiness. Past medical history significant is only for occasional gastrointestinal distress over the past 5 years. The young woman reports 3 sexual partners in the last six months. The physician notes that the patient was unable to release her grip after shaking hands. Which of the following techniques would allow a pathologist to confirm the diagnosis from a sample of the patient’s DNA?]]
Answer A	[[AnswerA::Northern blot; 5’(CAG)n3’ probe]]
Answer A Explanation	AnswerAExp::
Answer B	[[AnswerB::Northern blot; 5’(CTG)n3’ probe]]
Answer B Explanation	AnswerBExp::
Answer C	[[AnswerC::Southern blot; 5’(CAG)n3’ probe]]
Answer C Explanation	AnswerCExp::
Answer D	[[AnswerD::Southern blot; 5’(CTG)n3’ probe]]
Answer D Explanation	AnswerDExp::
Answer E	[[AnswerE::Southern blot; 5’(CAA)n3’ probe]]
Answer E Explanation	AnswerEExp::
Right Answer	RightAnswer::
Explanation	[[Explanation:: Educational Objective: References: ]]
Approved	Approved::No
Keyword
Linked Question	Linked::
Order in Linked Questions	LinkedOrder::