WBR242
| Author | PageAuthor::Gerald Chi |
|---|---|
| Exam Type | ExamType::USMLE Step 1 |
| Main Category | MainCategory::Pharmacology |
| Sub Category | SubCategory::Cardiology |
| Prompt | [[Prompt::A 58-year-old female comes to the clinic for a routine examination. She reports that she has started an antihypertensive drug recently. Physical examination is normal. Her blood pressure is 130/80 and laboratory studies show total cholesterol 220 mg/dl, LDL 100 mg/dl, HDL 50 mg/dl, triglyceride 350 mg/dl. She states that she has never had abnormal lipid profiles. Which of the following medications is most likely to cause her dyslipidemia?]] |
| Answer A | AnswerA::Prazosin |
| Answer A Explanation | [[AnswerAExp::Incorrect Prazosin is an alpha1-adrenergic antagonist and can cause side effects of orthostatic hypotension and nasal congestion.]] |
| Answer B | AnswerB::Lisinopril |
| Answer B Explanation | [[AnswerBExp::Incorrect Lisinopril is an angiotensin-converting enzyme inhibitor and may cause dry cough and hyperkalemia.]] |
| Answer C | AnswerC::Clonidine |
| Answer C Explanation | [[AnswerCExp::Incorrect Clonidine is a centrally acting alpha2-agonist and has the adverse effects of lightheadednes, dry mouth, dizziness, constipation, and hypotension.]] |
| Answer D | AnswerD::Atenolol |
| Answer D Explanation | [[AnswerDExp::Correct Atenolol is a non-selective beta blocker and may cause dyslipidemia.]] |
| Answer E | AnswerE::Verapamil |
| Answer E Explanation | [[AnswerEExp::Incorrect Verapamil is a non-dihydropyridine calcium channel blocker which has vasodilatory and negative inotropic, chronotropic, and dromotropic effects. Common side effects are dizziness, constipation, gastroesophageal reflux, and peripheral edema.]] |
| Right Answer | RightAnswer::D |
| Explanation | [[Explanation::Adverse effects associated with β2-adrenergic antagonism include bronchospasm, peripheral vasoconstriction, and alteration of glucose and lipid metabolism. Educational Objective: |
| Approved | Approved::No |
| Keyword | |
| Linked Question | Linked:: |
| Order in Linked Questions | LinkedOrder:: |