WBR255
Author | PageAuthor::Gerald Chi |
---|---|
Exam Type | ExamType::USMLE Step 1 |
Main Category | MainCategory::Pathology |
Sub Category | SubCategory::Musculoskeletal/Rheumatology |
Prompt | [[Prompt::A 48-year-old female visits the clinic for evaluation of her skin conditions. She has patches of hardened skin on her face, elbows, and knees. She feels that her fingers are tight especially in cold weathers, and become pallor and cyanotic and turn red and tingle. She also complains of difficulty in swallowing with regurgitation of food. Laboratory findings are notable for the presence nucleolar pattern of anti-nuclear antibodies as well as anti-centromere antibodies. Which of the following conditions is most likely to be associated with her illness?]] |
Answer A | AnswerA::Renal tubular acidosis |
Answer A Explanation | [[AnswerAExp::Incorrect CREST syndrome is not typically associated with renal tubular acidosis.]] |
Answer B | AnswerB::Primary sclerosing cholangitis |
Answer B Explanation | [[AnswerBExp::Incorrect CREST syndrome is not typically associated with primary sclerosing cholangitis.]] |
Answer C | AnswerC::Libman-Sacks endocarditis |
Answer C Explanation | [[AnswerCExp::Incorrect CREST syndrome is not typically associated with Libman-Sacks endocarditis.]] |
Answer D | AnswerD::Membranous glomerulonephritis |
Answer D Explanation | [[AnswerDExp::Incorrect CREST syndrome is not typically associated with membranous glomerulonephritis.]] |
Answer E | AnswerE::Pulmonary hypertension |
Answer E Explanation | [[AnswerEExp::Correct CREST syndrome may be associated with pulmonary hypertension.]] |
Right Answer | RightAnswer::E |
Explanation | [[Explanation::The limited cutaneous form of systemic sclerosis (lcSSc) is often referred to as CREST syndrome which is an acronym for the five main features: Calcinosis, Raynaud's syndrome, Esophageal dysmotility, Sclerodactyly, and Telangiectasia. Educational Objective: |
Approved | Approved::No |
Keyword | |
Linked Question | Linked:: |
Order in Linked Questions | LinkedOrder:: |