High density lipoprotein historical perspective
|
High Density Lipoprotein Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Clinical Trials |
|
Case Studies |
|
High density lipoprotein historical perspective On the Web |
|
American Roentgen Ray Society Images of High density lipoprotein historical perspective |
|
Risk calculators and risk factors for High density lipoprotein historical perspective |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Historical Perspective
Historically, beginning in the late 1970's cholesterol and lipid assays were promoted to estimate total HDL-cholesterol because such tests used to be far less expensive, by about 50 fold, than measured lipoprotein particle concentrations and subclass analysis. Over time, with continued research, decreasing costs, greater availability and wider acceptance of other "lipoprotein subclass analysis" assay methods, including NMR spectroscopy, human studies have continued to show a stronger correlation between human clinically obvious cardiovascular events and quantitatively measured large HDL-particle concentrations.[1]
References
- ↑ Umemoto T, Han CY, Mitra P; et al. (2013). "Apolipoprotein A-I and HDL Have Anti-Inflammatory Effects onAdipocytes via Cholesterol Transporters: ATP-Binding Cassette (ABC) A-1, ABCG-1 and Scavenger Receptor B-1(SRB-1)". Circulation Research. doi:10.1161/CIRCRESAHA.111.300581. PMID 23501697. Unknown parameter
|month=ignored (help)