High HDL definition
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High Density Lipoprotein Microchapters |
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High HDL definition On the Web |
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American Roentgen Ray Society Images of High HDL definition |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ;Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]
Overview
Based on the physiological action of High density lipoprotein particles by removing the fats from cells and deliver it to liver to be excreted, many studies admitted the inverse relation between HDL level and the risk of cardiovascular diseases.
Definition
Many large studies and clinical trials have been done to prove the inverse relation between HDL and the risk of cardiovascular diseases,[1][2] and the fact that more increase in HDL level improves the cardiovascular health.[3] The serum HDL level Goals for Patients at Risk of cardiovascular disease is recommended to be as high as possible, but at least ≥40 mg/dL in both men and women. Many debate about the serum level at which the risk of cardiovascular disease occurrence decline, an HDL value of ≥60 mg/dL is considered protective against heart disease according to latest guidelines.
Guideline Resource
https://www.aace.com/files/lipid-guidelines.pdf
References
- ↑ Gotto AM, Whitney E, Stein EA, Shapiro DR, Clearfield M, Weis S; et al. (2000). "Relation between baseline and on-treatment lipid parameters and first acute major coronary events in the Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS)". Circulation. 101 (5): 477–84. PMID 10662743.
- ↑ Emerging Risk Factors Collaboration. Di Angelantonio E, Sarwar N, Perry P, Kaptoge S, Ray KK; et al. (2009). "Major lipids, apolipoproteins, and risk of vascular disease". JAMA. 302 (18): 1993–2000. doi:10.1001/jama.2009.1619. PMC 3284229. PMID 19903920. Review in: Ann Intern Med. 2010 Feb 16;152(4):JC-212
- ↑ Sirtori, Cesare R. (October 2006). "HDL and the progression of atherosclerosis: new insights". European Heart Journal Supplements.