WBR0316

Author	[[PageAuthor::Ogheneochuko Ajari, MB.BS, MS [1]]]
Exam Type	ExamType::USMLE Step 1
Main Category	MainCategory::Embryology
Sub Category	SubCategory::Reproductive
Prompt	Prompt::In normal female development, the genital tubercle gives rise to the glans clitoris. In the male, the faulty positioning of the genital tubercle would give rise to?
Answer A	AnswerA::Hydrocele of the testis
Answer A Explanation	AnswerAExp::Incorrect. Hydrocele of the testis is as a result of the development of a fluid-filled sac within the scrotum that results from incomplete obliteration of the processus vaginalis
Answer B	AnswerB::Cryptoorchidism
Answer B Explanation	AnswerBExp::Incorrect. Cryptoorchidism result from the failure of the fetal testis to descend into the scrotum
Answer C	AnswerC::Bifid scrotum
Answer C Explanation	AnswerCExp::Incorrect. Bifid scrotum is due to malunion of the labioscrotal folds, which forms the labia majora in females
Answer D	AnswerD::Hypospadias
Answer D Explanation	AnswerDExp::Incorrect. Hypospadias result from abnormal opening of penile urethra on inferior (ventral) side of the penis due to failure of the urethral folds to close
Answer E	AnswerE::Epispadias
Answer E Explanation	AnswerEExp::Correct. See Explanation
Right Answer	RightAnswer::E
Explanation	[[Explanation::In normal fetal development, the genital tubercle gives rise to the glans clitoris and vestibular bulbs in the female and the glans penis and corpus carvernosum in males. The abnormal opening of the penile urethra on superior (dorsal) side of the penis due to faulty positioning of the genital tubercle give rise to Epispadias (Choice E). Extrophy of the bladder is associated with Epispadias. Educational Objective Epispadias arise due to the faulty positioning of the genital tubercle during development of the glans penis Reference: First AID for the USMLE Step 1 2013 Pg 513 Educational Objective: References: ]]
Approved	Approved::Yes
Keyword	WBRKeyword::Fetal development, WBRKeyword::genital tubercle, WBRKeyword::glans clitoris, WBRKeyword::glans penis
Linked Question	Linked::
Order in Linked Questions	LinkedOrder::