Low LDL causes

Low Density Lipoprotein Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Rim Halaby, M.D. [3]; Vendhan Ramanujam M.B.B.S [4]

Causes

Life Threatening Causes

Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.

Causes by Organ System

Cardiovascular	No underlying causes
Chemical/Poisoning	No underlying causes
Dental	No underlying causes
Dermatologic	Dyskeratosis congenita, lipomatosis of Madelung
Drug Side Effect	Clofibrate, colesevelam hydrochlorie, colestyramine, doxazosin, nicotinic acid, NSAID, prazosin, probucol, statins
Ear Nose Throat	No underlying causes
Endocrine	No underlying causes
Environmental	Ketogenic diet, malnutrition
Gastroenterologic	Celiac disease, chronic liver disease, chronic pancreatitis, cirrhosis, Crohn's disease, exocrine pancreatic insufficiency, intestinal lymphangiectasia, liver failure, portosystemic shunts, protein losing enteropathy, short bowel syndrome
Genetic	Abetalipoproteinemia, apolipoprotein B deficiency, Bassen-Kornzweig disease, cystic fibrosis, deficiency of proprotein convertase subtilisin-like/kexin type 9, dyskeratosis congenita, familial alphalipoprotein deficiency, familial hypobetalipoproteinemia, hyperlipoproteinemia, familial type 5, hypobetalipoproteinemia, lipoprotein lipase deficiency, mutations of the MTTP gene, Shwachman-Diamond syndrome
Hematologic	Acute myeloid leukemia
Iatrogenic	Portosystemic shunts, Short bowel syndrome
Infectious Disease	Giardiasis
Musculoskeletal/Orthopedic	No underlying causes
Neurologic	No underlying causes
Nutritional/Metabolic	Abetalipoproteinemia, apolipoprotein B deficiency, Bassen-Kornzweig disease, familial alphalipoprotein deficiency, familial hypobetalipoproteinemia, hyperlipoproteinemia, familial type 5, hypobetalipoproteinemia, lipoprotein lipase deficiency, mutations of the MTTP gene
Obstetric/Gynecologic	No underlying causes
Oncologic	Acute myeloid leukemia, malignancy
Ophthalmologic	No underlying causes
Overdose/Toxicity	No underlying causes
Psychiatric	No underlying causes
Pulmonary	No underlying causes
Renal/Electrolyte	No underlying causes
Rheumatology/Immunology/Allergy	Acute phase proteins, amyloidosis, autoimmune diseases, celiac disease, inflammatory cytokines, serum amyloid A, Sjrogren's syndrome
Sexual	No underlying causes
Trauma	No underlying causes
Urologic	No underlying causes
Miscellaneous	No underlying causes

Causes in Alphabetical Order

• Abetalipoproteinemia
• Acute myeloid leukemia
• Acute phase proteins
• Amyloidosis
• Apolipoprotein B deficiency
• Autoimmune diseases
• Bassen-Kornzweig disease
• Celiac disease
• Chronic liver disease
• Chronic pancreatitis
• Cirrhosis
• Clofibrate
• Colesevelam hydrochlorie
• Colestyramine
• Crohn's disease
• Cystic fibrosis

• Deficiency of proprotein convertase subtilisin-like/kexin type 9
• Doxazosin
• Dyskeratosis congenita
• Exocrine pancreatic insufficiency
• Familial alphalipoprotein deficiency
• Familial hypobetalipoproteinemia
• Giardiasis
• Hyperlipoproteinemia, familial type 5
• Hypobetalipoproteinemia
• Inflammatory cytokines
• Intestinal lymphangiectasia
• Ketogenic diet
• Lipomatosis of Madelung
• Lipoprotein lipase deficiency
• Liver failure

• Malignancy
• Malnutrition
• Ménétrier's disease
• Mutations of the MTTP gene
• Nicotinic acid
• NSAID
• Portosystemic shunts
• Prazosin
• Probucol
• Protein losing enteropathy
• Serum amyloid A
• Short bowel syndrome
• Shwachman-Diamond syndrome
• Sjrogren's syndrome
• Statins

References

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