Low VLDL causes

	Very Low Density Lipoprotein Microchapters
Home
Patient information
Overview
Historical Perspective
Classification
Biochemistry
Physiology
Clinical Correlation
High VLDL Definition Epidemiology and Demographics Pathophysiology Causes Prognosis and Complications
Low VLDL Definition Epidemiology and Demographics Pathophysiology Causes Prognosis and Complications
Treatment
Medical Therapy
Primary Prevention
Secondary Prevention
Landmark Trials
Future or Investigational Therapies
Case Studies
Case #1
Low VLDL causes On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Low VLDL causes All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Low VLDL causes
CDC on Low VLDL causes
Low VLDL causes in the news
Blogs on Low VLDL causes
Directions to Hospitals Treating Very low density lipoprotein
Risk calculators and risk factors for Low VLDL causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mugilan Poongkunran M.B.B.S [2]

Overview

Inherited disorders of lipoprotein metabolism like Abetalipoproteinemia and lipid lowering medications and diet are usually associated with low VLDL levels.

Causes

Life Threatening Causes

Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.

Common Causes

Causes by Organ System

Cardiovascular	No underlying causes
Chemical/Poisoning	No underlying causes
Dental	No underlying causes
Dermatologic	Dyskeratosis congenita, lipomatosis of Madelung
Drug Side Effect	Cilostazol, clofibrate, colestyramine, doxazosin, nicotinic acid, prazosin, probucol, statins
Ear Nose Throat	No underlying causes
Endocrine	No underlying causes
Environmental	Ketogenic diet, malnutrition
Gastroenterologic	Celiac disease, chronic liver disease, chronic pancreatitis, cirrhosis, Crohn's disease, exocrine pancreatic insufficiency, intestinal lymphangiectasia, liver failure, portosystemic shunts, protein losing enteropathy, short bowel syndrome
Genetic	Abetalipoproteinemia, apolipoprotein B deficiency, Bassen-Kornzweig disease, cystic fibrosis, deficiency of proprotein convertase subtilisin-like/kexin type 9, familial alphalipoprotein deficiency, familial hypobetalipoproteinemia, hyperlipoproteinemia, familial type 5, hypobetalipoproteinemia, lipoprotein lipase deficiency, mutations of the MTTP gene, Shwachman-Diamond syndrome
Hematologic	No underlying causes
Iatrogenic	Portosystemic shunts, short bowel syndrome
Infectious Disease	Giardiasis, Hepatitis C
Musculoskeletal/Orthopedic	No underlying causes
Neurologic	Parkinson's disease
Nutritional/Metabolic	Abetalipoproteinemia, apolipoprotein B deficiency, Bassen-Kornzweig disease, familial alphalipoprotein deficiency, familial hypobetalipoproteinemia, hyperlipoproteinemia, familial type 5, hypobetalipoproteinemia, lipoprotein lipase deficiency, mutations of the MTTP gene, omega-3 polyunsaturated fatty acids, fish oil
Obstetric/Gynecologic	No underlying causes
Oncologic	Malignancy
Ophthalmologic	No underlying causes
Overdose/Toxicity	No underlying causes
Psychiatric	No underlying causes
Pulmonary	No underlying causes
Renal/Electrolyte	No underlying causes
Rheumatology/Immunology/Allergy	Amyloidosis, autoimmune diseases, celiac disease, Sjögren's syndrome
Sexual	No underlying causes
Trauma	No underlying causes
Urologic	No underlying causes
Miscellaneous	No underlying causes

Causes in Alphabetical Order

References

↑ Scanu, AM.; Aggerbeck, LP.; Kruski, AW.; Lim, CT.; Kayden, HJ. (1974). "A study of the abnormal lipoproteins in abetalipoproteinemia". J Clin Invest. 53 (2): 440–53. doi:10.1172/JCI107578. PMID 11344558. Unknown parameter |month= ignored (help)
↑ Welty, FK.; Mittleman, MA.; Wilson, PW.; Sutherland, PA.; Matheney, TH.; Lipinska, I.; Muller, JE.; Levy, D.; Tofler, GH. (1997). "Hypobetalipoproteinemia is associated with low levels of hemostatic risk factors in the Framingham offspring population". Circulation. 95 (4): 825–30. PMID 9054738. Unknown parameter |month= ignored (help)
↑ Kim HJ, Moon JH, Kim HM, Yun MR, Jeon BH, Lee B; et al. (2013). "The hypolipidemic effect of cilostazol can be mediated by regulation of hepatic low-density lipoprotein receptor-related protein 1 (LRP1) expression". Metabolism. doi:10.1016/j.metabol.2013.09.006. PMID 24139096.
↑ Rojas A, Del Campo JA, Maraver M, Aparcero R, García-Valdecasas M, Diago M; et al. (2013). "Hepatitis C virus infection alters lipid metabolism depending on IL28B polymorphism and viral genotype and modulates gene expression in vivo and in vitro". J Viral Hepat. doi:10.1111/jvh.12209. PMID 24188401.
↑ Wei Q, Wang H, Tian Y, Xu F, Chen X, Wang K (2013). "Reduced serum levels of triglyceride, very low density lipoprotein cholesterol and apolipoprotein B in Parkinson's disease patients". PLoS One. 8 (9): e75743. doi:10.1371/journal.pone.0075743. PMC 3784418. PMID 24086623.

Template:WikiDoc Sources

[Scanu-1974-1] Scanu, AM.; Aggerbeck, LP.; Kruski, AW.; Lim, CT.; Kayden, HJ. (1974). "A study of the abnormal lipoproteins in abetalipoproteinemia". J Clin Invest. 53 (2): 440–53. doi:10.1172/JCI107578. PMID 11344558. Unknown parameter |month= ignored (help)

[Welty-1997-2] Welty, FK.; Mittleman, MA.; Wilson, PW.; Sutherland, PA.; Matheney, TH.; Lipinska, I.; Muller, JE.; Levy, D.; Tofler, GH. (1997). "Hypobetalipoproteinemia is associated with low levels of hemostatic risk factors in the Framingham offspring population". Circulation. 95 (4): 825–30. PMID 9054738. Unknown parameter |month= ignored (help)

[pmid24139096-3] Kim HJ, Moon JH, Kim HM, Yun MR, Jeon BH, Lee B; et al. (2013). "The hypolipidemic effect of cilostazol can be mediated by regulation of hepatic low-density lipoprotein receptor-related protein 1 (LRP1) expression". Metabolism. doi:10.1016/j.metabol.2013.09.006. PMID 24139096.

[pmid24188401-4] Rojas A, Del Campo JA, Maraver M, Aparcero R, García-Valdecasas M, Diago M; et al. (2013). "Hepatitis C virus infection alters lipid metabolism depending on IL28B polymorphism and viral genotype and modulates gene expression in vivo and in vitro". J Viral Hepat. doi:10.1111/jvh.12209. PMID 24188401.

[pmid24086623-5] Wei Q, Wang H, Tian Y, Xu F, Chen X, Wang K (2013). "Reduced serum levels of triglyceride, very low density lipoprotein cholesterol and apolipoprotein B in Parkinson's disease patients". PLoS One. 8 (9): e75743. doi:10.1371/journal.pone.0075743. PMC 3784418. PMID 24086623.

[1]

[2]

[3]

[4]

[5]

v t e Lipopedia
Basic Science	Cholesterol • Triglyceride Lipoprotein metabolism and transport Lipoprotein: Chylomicron • Chylomicron remnant • HDL • IDL • LDL • Lipoprotein(a) • VLDL • Lipoprotein-X Apolipoprotein: APOA (1, 2, 4, 5) • APOB ( Apolipoprotein B-48, Apolipoprotein B-100) • APOC (1, 2, 3, 4) • APOD • APOE • APOH • APOJ • APOL • APOM • Apo(a) Lipoprotein receptor: LDL receptor • Soluble low density lipoprotein receptor-related protein (sLRP) • Apolipoprotein E Receptor 2 • Scavenger receptor • Scavenger receptor A • Scavenger receptor B • VLDL receptor Lipoprotein enzymes: Lipoprotein lipase • Lipoprotein-associated phospholipase A2 (Lp-PLA2) • Cholesterylester transfer protein ( Acetyl-CoA C-acyltransferase, Lecithin-cholesterol acyltransferase) • Microsomal triglyceride transfer protein • ABCA1 Genes: Low density lipoprotein receptor gene family • Microsomal triglyceride transfer protein • ABCA1
Lipoprotein Disorders	Lipoprotein disorders Primary lipoprotein disorders: Familial hyperchylomicronemia (Type I) • Familial hypercholesterolemia (Type IIA) • Familial combined hyperlipidemia (Type IIB) • Dysbetalipoproteinemia (Type III) • Primary hypertriglyceridemia (Type IV) • Mixed hyperlipoproteinemia (Type V) Secondary lipoprotein disorders
Abnormal Laboratory Lipid Profile	Low chylomicron • Low chylomicron remnant • Low HDL • Low IDL • Low LDL • Low lipoprotein(a) • Low VLDL High chylomicron • High chylomicron remnant • High HDL • High IDL • High LDL • High Lipoprotein(a) • High VLDL