Polycystic kidney disease epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Serge Korjian, Yazan Daaboul
Overview
ADPKD affects approximately 1 in 1000 individuals although prevalence varies according to countries and certain microsattelite regions with a heavy concentration of PKD mutations.
Epidemiology and Demographics
ADPKD is a disorder found worldwide and in all ethnic groups. Prevalence is slightly lower in African Americans with fewer cases of ESRD attributed to ADPKD than in Caucasian or Asian individuals. Prevalence is roughly equal among males and females. The table below summarizes the estimated prevalence in selected countries based on available epidemiologic studies.[1]
| Country | Prevalence | Article |
| USA | 1 in 400-1000 | Iglesias et al, 1983[2] |
| Denmark | 1 in 1000 | Dalgaard, 1957[3] |
| Germany | 1 in 3058 | Neumann et al, 2013[4] |
| France | 1 in 1111 | Simon et al, 1996[5] |
| United Kingdom | 1 in 2459 | Davies et al, 1991[6] |
| Japan | 1 in 4033 | Higashihara et al, 1998[7] |
References
- ↑ Torres VE, Harris PC, Pirson Y (2007). "Autosomal dominant polycystic kidney disease". Lancet. 369 (9569): 1287–301. doi:10.1016/S0140-6736(07)60601-1. PMID 17434405.
- ↑ Iglesias CG, Torres VE, Offord KP, Holley KE, Beard CM, Kurland LT (1983). "Epidemiology of adult polycystic kidney disease, Olmsted County, Minnesota: 1935-1980". Am J Kidney Dis. 2 (6): 630–9. PMID 6846334.
- ↑ DALGAARD OZ (1957). "Bilateral polycystic disease of the kidneys; a follow-up of two hundred and eighty-four patients and their families". Acta Med Scand Suppl. 328: 1–255. PMID 13469269 Check
|pmid=value (help). - ↑ Neumann HP, Jilg C, Bacher J, Nabulsi Z, Malinoc A, Hummel B; et al. (2013). "Epidemiology of autosomal-dominant polycystic kidney disease: an in-depth clinical study for south-western Germany". Nephrol Dial Transplant. 28 (6): 1472–87. doi:10.1093/ndt/gfs551. PMID 23300259.
- ↑ Simon P, Le Goff JY, Ang KS, Charasse C, Le Cacheux P, Cam G (1996). "[Epidemiologic data, clinical and prognostic features of autosomal dominant polycystic kidney disease in a French region]". Nephrologie. 17 (2): 123–30. PMID 8838759.
- ↑ Davies F, Coles GA, Harper PS, Williams AJ, Evans C, Cochlin D (1991). "Polycystic kidney disease re-evaluated: a population-based study". Q J Med. 79 (290): 477–85. PMID 1946928.
- ↑ Higashihara E, Nutahara K, Kojima M, Tamakoshi A, Yoshiyuki O, Sakai H; et al. (1998). "Prevalence and renal prognosis of diagnosed autosomal dominant polycystic kidney disease in Japan". Nephron. 80 (4): 421–7. PMID 9832641.