Febrile neutropenia resident survival guide
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Definition
Fever in a neutropenic patients is defined as one oral temperature of >38.3°C (101°F) or a temperature of >38.0°C (100.4°F) for >1 hour. Neutropenia is defined as an absolute neutrophil count (ANC) <1500 cells/microL. Severe neutropenia is defined when the ANC <500 cells/microL, or an ANC that is expected to decrease to <500 cells/microL over the next 48 hours. Clinically significant infections usually occurs with severe neutropenia
Causes
Life Threatening Causes
Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.
Common Causes
Management
Shown below is an algorithm summarizing the approach to [[disease name]].
| Fever > 101 or fever > 100.4 for 1 hour in patient with ANC <1500 | |||||||||||||||||||||||||||||||||
| Low risk of serious complications | High risk of serious complications | ||||||||||||||||||||||||||||||||