Iodoquinol
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
The quinoline derivative diiodohydroxyquinoline (INN) or iodoquinol (USAN) can be used in the treatment of amebiasis, balantidiasis, and Dientamoeba fragilis.[1] It is poorly absorbed from the gastrointestinal tract and is used as a luminal agent to eradicate both cysts and trophozoites infestating the lumen of the gastrointestinal tract. Iodoquinol is not recommended for prolonged use due to associated toxicities (eg, optic neuritis, optic atrophy, and peripheral neuropathy).
Category
Amebicide
US Brand Names
YODOXIN®
Package Insert
Description | Inactive Ingredients | Action | Indications | Contraindications | Warnings | Use in Pregnancy | Precautions | Adverse Reactions | Dosage and Administration | How Supplied | Storage
Mechanisms of Action
Iodoquinol acts by chelation of Fe2+ which is essential for metabolism.