Ceftizoxime
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{{Drugbox | IUPAC_name = (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | image = ceftizoxime.png
| tradename = Cefizox | Drugs.com = Consumer Drug Information | MedlinePlus = a684043 | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration =
| bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion =
| CAS_number = 68401-81-0 | CAS_supplemental = 68401-82-1 | ATC_prefix = J01 | ATC_suffix = DD07 | PubChem = 6533629 | DrugBank = | ChemSpiderID = 5018818 | UNII_Ref = | UNII = C43C467DPE | KEGG = D07658 | ChEMBL = 528
| C=13 | H=13 | N=5 | O=5 | S=2 | molecular_weight = 383.405 g/mol }}
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Ceftizoxime is a third-generation cephalosporin available for parenteral administration.
Unlike other 3rd generation cephalosporins, in ceftizoxime the whole C-3 side chain has been removed to prevent deactivation by hydrolytic enzymes. It rather resembles cefotaxime in its properties, but is not subjected to metabolism.
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