Adefovir overdosage
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overdosage
Doses of adefovir dipivoxil 500 mg daily for 2 weeks and 250 mg daily for 12 weeks have been associated with gastrointestinal side effects. If overdose occurs the patient must be monitored for evidence of toxicity, and standard supportive treatment applied as necessary.
Following a 10 mg single dose of HEPSERA, a four-hour hemodialysis session removed approximately 35% of the adefovir dose.[1]
References
- ↑ "http://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021449s020lbl.pdf" (PDF). External link in
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Adapted from the FDA Package Insert.