Clarithromycin
Synonyms / Brand Names: CLA, Clarithromycine, Clathromycin, Biaxin, Biaxin XL, Klacid, Klaricid, Macladin, Naxy, Veclam, Zeclar
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Dosing and Administration
BIAXIN Filmtab (clarithromycin tablets, USP) and BIAXIN Granules (clarithromycin for oral suspension, USP) may be given with or without food. BIAXIN XL Filmtab (clarithromycin extended-release tablets) should be taken with food. BIAXIN XL tablets should be swallowed whole and not chewed, broken or crushed.
Adult dosage guidelines
For pharyngitis/tonsillitis due to S. pyogenes:
- 250 mg (q12h) of BIAXIN tablets should be given for a duration of 10 days.
For acute maxillary sinusitis due to H. influenzae, M. catarrhalis, and/or S. pneumonia:
- 500 mg (q12h) of BIAXIN tablets should be given for a duration of 14 days or
- 2 x 500 mg (q24h) of BIAXIN XL tablets should be given for a duration of 14 days.
For acute exacerbation of chronic bronchitis due to H. influenzae, M catarrhalis, and/or S. pneumoniae:
- 500 mg (q12h) of BIAXIN tablets should be given for a duration of 7-14 days or
- 2 x 500 mg (q24h) of BIAXIN XL tablets should be given for a duration of 7 days.
For acute exacerbation of chronic bronchitis due to H. parainfluenzae:
- 500 mg (q12h) of BIAXIN tablets should be given for a duration of 7 days or
- 2 x 500 mg (q24h) of BIAXIN XL tablets should be given for a duration of 7 days.
For community-acquired pneumonia due to H. influenzae:
- 250 mg (q12h) of BIAXIN tablets should be given for a duration of 7 days or
- 2 x 500 mg (q24h) of BIAXIN XL tablets should be given for a duration of 7 days.
For community-acquired pneumonia due to H. parainfluenzae and/or M. catarrhalis:
- 2 x 500 mg (q24h) of BIAXIN XL tablets should be given for a duration of 7 days.
For community-acquired pneumonia due to S. pneumoniae, C. pneumoniae, and/or M. pneumoniae:
- 250 mg (q12h) of BIAXIN tablets should be given for a duration of 7-14 days or
- 2 x 500 mg (q24h) of BIAXIN XL tablets should be given for a duration of 7 days.
For uncomplicated skin and skin structure due to S. aureus and/or S.pyogenes:
- 250 mg (q12h) of BIAXIN tablets should be given for a duration of 7 days.
For further dosage and administration instructions see Instructions for Administration.
FDA Package Insert Resources
Indications, Contraindications, Side Effects, Drug Interactions, etc.
Calculate Creatine Clearance
On line calculator of your patients Cr Cl by a variety of formulas.
Convert pounds to Kilograms
On line calculator of your patients weight in pounds to Kg for dosing estimates.
Publication Resources
Recent articles, WikiDoc State of the Art Review, Textbook Information
Trial Resources
Ongoing Trials, Trial Results
Guidelines & Evidence Based Medicine Resources
US National Guidelines, Cochrane Collaboration, etc.
Media Resources
Slides, Video, Images, MP3, Podcasts, etc.
Patient Resources
Discussion Groups, Handouts, Blogs, News, etc.
International Resources
en Español
FDA Package Insert Resources
Indications
Contraindications
Side Effects
Drug Interactions
Precautions
Overdose
Instructions for Administration
How Supplied
Pharmacokinetics and Molecular Data
FDA label
FDA on Clarithromycin
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Publication Resources
Most Recent Articles on Clarithromycin
Review Articles on Clarithromycin
Articles on Clarithromycin in N Eng J Med, Lancet, BMJ
WikiDoc State of the Art Review
Textbook Information on Clarithromycin
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Trial Resources
Ongoing Trials with Clarithromycin at Clinical Trials.gov
Trial Results with Clarithromycin
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Guidelines & Evidence Based Medicine Resources
US National Guidelines Clearinghouse on Clarithromycin
Cochrane Collaboration on Clarithromycin
Cost Effectiveness of Clarithromycin
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Media Resources
Powerpoint Slides on Clarithromycin
Images of Clarithromycin
Podcasts & MP3s on Clarithromycin
Videos on Clarithromycin
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Patient Resources
Patient Information from National Library of Medicine
Patient Resources on Clarithromycin
Discussion Groups on Clarithromycin
Patient Handouts on Clarithromycin
Blogs on Clarithromycin
Clarithromycin in the News
Clarithromycin in the Marketplace
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International Resources
Clarithromycin en Español
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Adapted from the FDA Package Insert.