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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rim Halaby, M.D. [2]

Overview

Sepsis is a life threatening condition.[1][2]

Title

References

  1. XYZ, NEJM, 2014
  2. Remick DG (2007). "Pathophysiology of sepsis". Am J Pathol. 170 (5): 1435–44. doi:10.2353/ajpath.2007.060872. PMC 1854939. PMID 17456750.


 
 
 
Characterize the symptoms:
❑ Diffuse bleeding
❑ Jaundice
❑ Dyspnea
❑ Delirium
❑ Coma
Obtain medical history:
❑ Prior thromboses
❑ Known hypercoagulability
❑ Known hemostatic defect
 
 
 
 
 
 
 
 
 
 
 
 
Examine the patient:
❑ Digital ischemia
❑ Hypotension
❑ Fever
❑ Acral cyanosis
❑ Bleeding from wounds/puncture sites
❑ Petechiae
❑ Purpura
Rash
❑ Ecchymosis
❑ Bedside Observations
 :❑ Stroke
 :❑ Acute MI
 :❑ ARF
 :❑ DVT
 :❑ PE
 :❑ Purpura fulminans
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Order tests:
Peripheral blood smear
 :❑ ↓Platelet count
 :❑ + Schistocytes
❑ Clotting screen
❑ ↑PT
❑ ↑aPTT
❑ ↓Fibrinogen
❑ ↓Haptoglobin
❑ +D-dimer
Other Investigations