Multiple myeloma differential diagnosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
It needs to be differentiated from other blood cell disorders as well as bony neoplasms and metastasis.
Differentiating Muliple Myeloma from other Diseases
- Diseases with similar symptoms
- Bone fracture - this includes lytic bone tumors such as:
- Fibrous dysplasia
- Enchondroma
- Eosinophilic granuloma
- Giant cell tumor
- Osteoblastoma
- Aneurysmal Bone Cyst
- Solitary Bone Cyst
- Hyperparathyroidism
- Infection
- Chondroblastoma
- Chondromyxoid Fibroma
- Reactive plasmacytosis
- Macroglobulinemia
- Bone metastatic tumor
- Other plasma cell disorders such as:
- Monoclonal Gammopathies of Uncertain Origin
- Waldenstrom Hypergammaglobulinemia