Diltiazem Hydrochloride injection nonclinical toxicology
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Abdurahman Khalil, M.D. [2]
NONCLINICAL TOXICOLOGY
Carcinogenesis, Mutagenesis, Impairment of Fertility
A 24-month study in rats and a 21-month study in mice showed no evidence of carcinogenicity. There was also no mutagenic response in in vitro bacterial tests. No intrinsic effect on fertility was observed in rats.[1]
References
- ↑ "DILTIAZEM HYDROCHLORIDE INJECTION [AKORN, INC.]". Retrieved 5 March 2014.