Magnesium sulfate (injection)

Magnesium sulfate
MAGNESIUM SULFATE® FDA Package Insert
Indications and Usage
Dosage and Administration
Contraindications
Warnings and Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Overdosage
Clinical Pharmacology
How Supplied/Storage and HandlingInformation]]
Labels and Packages
Clinical Trials on Magnesium sulfate
ClinicalTrials.gov

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2]

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Synonyms / Brand Names: Magnesium sulfate

Overview

Magnesium sulfate (or magnesium sulphate) is an inorganic salt (chemical compound) containing magnesium, sulfur and oxygen, with the formula MgSO₄. It is often encountered as the heptahydrate sulfate mineral epsomite (MgSO₄·7H₂O), commonly called Epsom salt, taking its name from a bitter saline spring in Epsom in Surrey, England, where the salt was produced from the springs that arise where the porous chalk of the North Downs meets non-porous London clay. The monohydrate, MgSO₄·H₂O is found as the mineral kieserite. The overall global annual usage in the mid 1970s of the monohydrate was 2.3 million tons, of which the majority as used in agriculture.

Category

Purgative Laxative and Antiarrythmics

FDA Package Insert

| Indications and Usage | Dosage and Administration | Dosage Forms and Strengths | Contraindications | Warnings and Precautions | Adverse Reactions | Drug Interactions | Use in Specific Populations | Overdosage | Description | Clinical Pharmacology | Nonclinical Toxicology | Clinical Studies | How Supplied/Storage and Handling | Patient Counseling Information | Labels and Packages

Mechanism of Action

Magensium has a role factor in more than 300 enzymatic reactions. It is involved in many processes as hormone receptor binding, gating of calcium channels, transmembrane ion flux and regulation of adenylate cyclase. It has role in muscle contraction, vasomotor tone, cardiac excitability and neural activity.