Fragmin injection/adult indications and dosage

Fragmin injection®
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Adult Indications and Dosage
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

FDA-Labeled Indications and Dosage (Adult)

• Prophylaxis of Venous Thromboembolism Following Abdominal Surgery

Recommneded dose: 2500 IU SUBQ q24h (starting 1 to 2 hours prior to surgery) for 5 to 10 days.

High risk of thromboembolic complications: 5000 IU SUBQ q24h (starting the evening prior to surgery) for 5 to 10 days OR 2500 IU SUBQ 1 to 2 hours prior to surgery followed by 2500 IU 12 hours later and 5000 IU q24h thereafter for 5 to 10 days

• Acute coronary syndrome, Associated with unstable angina or non-Q-wave myocardial infarction - Myocardial ischemia; Prophylaxis
• Cancer - Venous thromboembolism
• Deep venous thrombosis, In medical patients with severely restricted mobility due to acute illness; Prophylaxis
• Postoperative deep vein thrombosis; Prophylaxis - Total replacement of hip

Infection Preferred Regimen ▸ Drug A 50 mg/kg IV q8h PLUS ▸ Drug B 50 mg/kg IV q8—12h Alternative Regimen ▸ Drug C 50 mg/kg IV q8h PLUS ▸ Drug D 2.5 mg/kg IV q8h OR ▸ Drug E 2.5 mg/kg IV q8h